Seaport Hotel from Logan Airport
For people staying at the Seaport Hotel, it looks like it's really easy to get there from the airport if you take the Subway. You just get on the Silver line at the airport and stay on it until World Trade Center Station.
Here is the MBTA page about the Silver Line and here are directions to the hotel from their webpage.
Here is the MBTA page about the Silver Line and here are directions to the hotel from their webpage.